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This book opens up a new approach for clinicians, already bombarded with an overwhelming amount of information, and wanting to apply evidence-based medicine. Unlike usual sequential analysis of clinical trials, this book brings into sharp focus the essential points of more than 400 clinical studies. The central themes derived from this cross-sectional analysis constitute a modern overview of cardiovascular therapeutics.
|TAILLE DU FICHIER||1,46 MB|
|DATE DE PUBLICATION||1999-Oct-01|
Over the past 15 years, the proportion of clinical research sponsored by the pharmaceutical industry has increased and likely will continue to expand A cross-sectional analysis of HIV and hepatitis C clinical trials 2007 to 2010: the relationship between industry sponsorship and randomized study design | springermedizin.de
We included data from three identified trials and 34 322 patients (60·2% with established atherosclerotic cardiovascular disease), with 3342 major adverse cardiovascular events, 2028 cardiovascular deaths or hospitalisation sfor heart failure events, and 766 renal composite outcomes. SGLT2i reduced major adverse cardiovascular events by 11% (HR 0·89 [95% CI 0·83-0·96], p=0·0014), with ...